منابع مشابه
Molecular Sensing Using Hyperpolarized Xenon NMR Spectroscopy
Although proton-based magnetic resonance imaging (MRI) provides a powerful modality for clinical imaging with excellent spatial resolution, it is not well suited to imaging void spaces (i.e., the lungs), low-abundance molecular markers of disease, or environments where unique proton spin densities are low. To address this limitation, hyperpolarized (hp) xenon-based NMR spectroscopy and MRI have...
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Hyperpolarized (129)Xe (HpXe) NMR not only holds promise for functional lung imaging, but for measurements of tissue perfusion as well. To investigate human brain perfusion, several time-series of (129)Xe MR spectra were recorded from one healthy volunteer after HpXe inhalation. The time-dependent amplitudes of the MR spectra were analyzed by using a compartment model for xenon uptake modified ...
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متن کاملHyperpolarized xenon for NMR and MRI applications.
Nuclear magnetic resonance (NMR) spectroscopy and imaging (MRI) suffer from intrinsic low sensitivity because even strong external magnetic fields of ~10 T generate only a small detectable net-magnetization of the sample at room temperature (1). Hence, most NMR and MRI applications rely on the detection of molecules at relative high concentration (e.g., water for imaging of biological tissue) o...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance
سال: 2011
ISSN: 1090-7807
DOI: 10.1016/j.jmr.2010.10.004